As a result of rapid changes affecting higher education, educators face continuing challenges to meet their responsibilities and must reevaluate their interactions with students, both inside and outside the classroom. This new issue examines how educators might mentor their students. Covering a variety of disciplines, the authors discuss how to prepare students for more active and collaborative learning and how to help students develop different skills they will need to succeed. They also examine the effect of changing demographics, diverse student populations, and changing student expectations on mentoring. In the transition to a learning-focused environment with the student at the center of the endeavor, instructors will find this issue a helpful tool as they continue to play a major but changing role. This is the 85th issue of the Jossey-Bass series New Directions for Teaching and Learning.