In the year 2038, an act of bioengineered terrorism decimated humanity. Those who survived were either completely unaffected or developed horrible mutations. Across the globe, nations are now divided between areas populated by "norms" and lands run by "mutants" - Detective Cassandra Lee of Los Angeles's Special Investigative Section has built a fierce reputation taking down some of the city's most notorious criminals. But the serial cop killer known as Bonebreaker - who murdered Lee's father - is still at large. Officially, she's too personally involved to work on the Bonebreaker case. Unofficially, she's going to hunt him to the ends of the earth.