Dynamic Combinatorial Chemistry (Innbundet)

in Drug Discovery, Bioorganic Chemistry, and Materials Science

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Innbinding: Innbundet
Utgivelsesår: 2008
Antall sider: 266
Forlag: John Wiley and Sons Ltd
Språk: Engelsk
ISBN/EAN: 9780470096031
Kategori: Naturvitenskap
Omtale Dynamic Combinatorial Chemistry
This book presents an overview of dynamic combinatorial chemistry (DCC) and fragment-based library methods and how chemists apply them to the problems of lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science. Chapters cover basic theory, approaches to binding in proteins and small molecules, molecular recognition, catalyst discovery, click chemistry, "SAR by NMR," and analytical chemistry challenges. A single-source reference about modern methods in fragment-based drug discovery and DCC methods and applications, this is a core resource for chemists building structure libraries and designing compounds.

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