A Handbook for DNA-encoded Chemistry (Innbundet)

Theory and Applications for Exploring Chemical Space and Drug Discovery

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Innbinding: Innbundet
Utgivelsesår: 2014
Antall sider: 480
Forlag: John Wiley & Sons Inc
Språk: Engelsk
ISBN/EAN: 9781118487686
Kategori: Teknologi, transport og landbruk
Omtale: A Handbook for DNA-encoded Chemistry
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available chemical space for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods

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