Drug Design of Zinc-Enzyme Inhibitors (Innbundet)

Functional, Structural, and Disease Applications

Serie: Wiley Series in Drug Discovery and Development 

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Innbinding: Innbundet
Utgivelsesår: 2009
Antall sider: 1022
Forlag: John Wiley and Sons Ltd
Språk: Engelsk
Serie: Wiley Series in Drug Discovery and Development
ISBN/EAN: 9780470275009
Kategori: Teknologi, transport og landbruk
Omtale: Drug Design of Zinc-Enzyme Inhibitors
The book gives students and young researchers a resource on zinc enzymes, some of which were intensively studied for more than six decades and translated into model success stories of the pharmaceutical industry. Up-to-date overviews on the major drug targets of the field are presented, showing the structural basis for catalysis, binding of inhibitors and activators, and their clinical applications. Emergent roles of some recently discovered isozymes in cancer, obesity, epilepsy, pain management, and malaria are also introduced, together with the most recent achievements in drug design from both academia and industry.

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