The third edition of "Karch's Pathology of Drug Abuse" continues to provide a comprehensive yet accessible guide to the pathology, toxicology, and pharmacology of commonly abused drugs. As in previous editions, the focus remains on the investigation of drug-related deaths and on practical approaches to the detection of drug abuse. It covers in detail the clinical consequences of drug usage and provides the latest information on clinical aspects of drug abuse. This well-written, extensively referenced resource supplies a mixture of clinical information and pathology findings.This title includes: new information on methamphetamine abuse; new chapter on GHB, ketamine, and select herbal hallucinogens; new micrographs showing pathology of drug related deaths; and, over 1000 new references. It describes: the mechanism of sudden death in cocaine users and overdose in heroin abusers; toxicology and pathology of ephedrine; neurochemistry of excited delirium; and, psychotic behavior in stimulant abusers.Steven B.Karch has appeared as an expert witness in international cases, including advice to counsel in the Harold Shipman murder trial.
He is an assistant medical examiner in San Francisco, where he consults on cases of drug-related deaths. He received his bachelors degree from Brown University, did graduate work in cell biology and biophysics at Stanford, and received his M.D. from Tulane University Medical School.